Notes
Outline
Keeping an Eye on HIV Fatigue and Wasting
Disclaimers
This is NOT a medical presentation
This material is not meant to substitute for medical advice
The opinions expressed here are solely of the person who gives them
The HIV Council does not endorse or oppose any products mentioned.
Working Assumptions
There are no simple solutions to complex problems
Each person has an idea of what healthy means, and that is their goal.
The goal of medicine should be to help a person look and feel better, as well as live for as long as possible.
It is possible to live long and well with HIV/AIDS
Working Model
Good Health Occurs when the body, mind, and spirit are in harmony with one another and the environment.
Medicine supports one or all of these axes to assist in natural healing processes.
Prevention
“An ounce of  prevention is worth a pound of cure”
The Humpty Dumpty Syndrome: (Dr. Lark Lands, Ph.D.)
Humpty Dumpty sat on a wall.
Humpty Dumpty had a great fall.
Miracles Happen !
Fatigue
Physical Fatigue
Mental Fatigue
Motivational Fatigue
A subjective (personal) experience of:
Low energy
Tired
Muscles feel heavy
Everything is an effort
Weakness
Fatigue Can Be VERY Serious
Or you just could be, plain tired
Don’t blow it off.
Get It Checked out
Find the CAUSE(s).
It is often Multi-Factorial (cause by more than one thing)
Fatigue Factors
Poor diet (food and water)
Drug/Alcohol
Lifestyle (exercise)
Not enough quality sleep
Psychological – Mental
HIV itself
HIV Medications
Infections
Glandular, Hormonal problems
Anemia (more of a symptom)
Muscle wasting (syndrome)
Things to Do
Get a full check up
Eat better, pure water
Get more sleep, and make sure your getting a good nights rest.
Exercise
Lifestyle adjustments
Medical Treatments
Find and Treat the causes
Psychological, Physical, and/or Environmental
Video
You Don’t Have to Feel This Way:  The facts about HIV – related fatigue
Wasting
Unintentional Weight Loss
More than 5% of body weight
Like 8.5 lbs for 170 lbs.
Not just about weight loss
Muscle tissue is burned instead of fat.
Related to fat redistribution
Fat moving toward the middle of the body from the periphery.
Starts before it becomes visible.
Wasting is Serious
“...The people who have died from HIV died not from the causes listed on their death certificates, but in fact, from wasting — starvation from within.”
Dr. Mary Romeyn, M.D.
Nutrition and HIV: A New Model For Treatment, 1998.
Research
Researchers  demonstrated a clear relation between weight loss and an increased risk of individual opportunistic complications.
“Our data demonstrate that weight loss of as little as 5% to 10% of body weight over 4 months is predictive of death and an increased risk of opportunistic complications, even those with no history of a previous or concurrent opportunistic complications.”
Wheeler DA, Gibert CL, Launer CA, et al. Weight Loss as a Predictor of Survival and Disease Progression in HIV Infection. J Acqui Immune Defic Syndr Hum Retrovirol 1998;18:80-5
The Leading Cause of death?
Multi-Factorial
Wasting Factors
HIV
Infections, parasites
HIV Medications
Hormonal deficiencies
Anything that effects your ability to ingest (eat) and digest (absorb) food.
Problems in the mouth and throat
GI infections, issues
Lifestyle: exercise, diet, addictions, habits, attitudes.
Ways to Measure
Monitor body weight
Body composition analysis
Bio-electric Impedance Analysis (BIA)
Measures muscle to fat ratios
Estimates Body Cell Mass (Lean Body Mass)
Estimates extracelluar and intracellular water.
BIA
In 1989 researchers concluded that the timing of death from AIDS wasting is related to the magnitude of body-cell-mass depletion.  “We concluded that the timing of death from wasting in AIDS is related to the magnitude of body-cell-mass depletion rather than the identity of the specific disease process that causes the depletion.”1
In 1994 researchers have found that Bioelectrical Impedance Analysis is one of the best predictors of survival in AIDS patients. “In our model the phase angle— was a better single predictor of survival than any other nutritional parameter tested (body weight, BMI, serum nutritional parameters) and was also superior to widely used CD4+ cell count.”2
BIA Results
BIA Video
Serono Patient Video
Prevention
Monitor weight and muscle to fat ratios
Good Nutrition
Quality Medical Management of HIV and related infections
Exercise
Plenty of R&R
Reduce negative stress
Lifestyle Adjustments
Treatment
Treat HIV and infections
Boost nutrition and ability to absorb nutrients
Quality Protein
Micro Nutrients (Vitamins)
Amino Acids (L-Glutamine…)
Digestive Enzymes
Friendly Bacteria (Acidophilus)
Anabolic Therapies
Growth Hormone
Conclusion
The good news is that there is a lot you can do to prevent and/or treat fatigue and unintentional weight loss.
The Goal is to stay out of the hospital.
Stay Healthy
Stay Strong
Keep Positive
Resources
Romeyn, Mary MD.  Nutrition and HIV: A New Model for Treatment. 1998
Kaiser, Jon D. MD.  Healing HIV: How to Rebuild Your Immune System. 1999
Mooney, Michael and Vergel, Nelson.  Built To Survive: A Comprehensive Guide to the Medical Use of Anabolic Steroids, Nutrition and Exercise for HIV (+) Men and Women. 1999
Acknowledgments
This presentation was made possible by an  unrestricted educational grant from Unimed Laboratories.